Welcome to the second in our blog series on Dr. Reid Hayward of the University of Northern Colorado.
As we mentioned in our first blog, Dr. Hayward is using rat models to study the protective effect of exercise on chemotherapy patients.
One of the side effects of chemotherapeutic treatment with doxorubicin is cardiotoxicity, limiting the effectiveness of drugs by weakening the patient before the treatment can eliminate the cancer. In the use of doxorubicin, cardiotoxicity has taken the form of a weakened heart, with the heart chambers enlarged, and the walls thinned. Physical activity has been shown to preserve the morphology of the heart during doxorubicin treatment giving the cancer patients a better chance of recovery.
In this video, Dr. Hayward talks about his lab’s findings around doxorubicin’s effects on heart morphology.