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A global analysis of low-complexity regions in the Trypanosoma brucei proteome reveals enrichment in the C-terminus of nucleic acid binding proteins providing potential targets of phosphorylation

A global analysis of low-complexity regions in the Trypanosoma brucei proteome reveals enrichment in the C-terminus of nucleic acid binding proteins providing potential targets of phosphorylation

Posted on December 10, 2020 by Christopher

Background: Low-complexity areas (LCRs) on proteins have attracted rising consideration not too long ago on account of their position within the meeting of membraneless organelles or granules by liquid-liquid section separation. A number of examples of such granules have been proven to sequester RNA and proteins in an inactive state, offering an vital mechanism for dynamic post-transcriptional gene regulation. In trypanosome parasites, post-transcriptional management overwhelmingly dominates gene regulation because of the organisation of their genome into polycistronic transcription items. The aim of the present research was to generate a considerably extra complete genome-wide survey of LCRs on trypanosome proteins than at present out there .

Strategies: Utilizing the Shannon’s entropy technique, supplied within the R bundle ‘entropy’, we recognized LCRs within the proteome of Trypanosoma brucei. Our evaluation predicts LCRs and their positional enrichment in distinct protein cohorts and superimposes on this a spread of post-translational modifications derived from out there experimental datasets.

Outcomes: Our outcomes spotlight the enrichment of LCRs within the C-terminal area of predicted nucleic acid binding proteins, these appearing as favoured websites for potential phosphorylation.

Conclusions: The post-translational modifications of LCRs, and particularly the phosphorylation occasions, may contribute to post-transcriptional gene expression management and the dynamics of protein concentrating on to membraneless organelles in kinetoplastid parasites.

 

Web site-Particular Phosphorylation of Histone H1.Four Is Related to Transcription Activation

 

Core histone variants, comparable to H2A.X and H3.3, serve specialised roles in chromatin processes that depend upon the genomic distributions and amino acid sequence variations of the variant proteins. Modifications of those variants alter interactions with different chromatin elements and thus the protein’s capabilities. These inferences add to the rising arsenal of proof towards the older generic view of these linker histones as redundant repressors.

Moreover, sure modifications of particular H1 variants can confer distinct roles. On the one hand, it has been reported that the phosphorylation of H1 ends in its launch from chromatin and the next transcription of HIV-1 genes. However, latest proof signifies that phosphorylated H1 could in truth be related to energetic promoters. This battle means that completely different H1 isoforms and modified variations of those variants aren’t redundant when collectively however could play distinct purposeful roles. Right here, we offer the primary genome-wide proof that when phosphorylated, the H1.Four variant stays related to energetic promoters and should even play a job in transcription activation. Utilizing novel, extremely particular antibodies, we generated the primary genome-wide view of the H1.Four isoform phosphorylated at serine 187 (pS187-H1.4) in estradiol-inducible MCF7 cells. We observe that pS187-H1.Four is enriched primarily on the transcription begin websites (TSSs) of genes activated by estradiol remedy and depleted from these which can be repressed. We additionally present that pS187-H1.

Four associates with ‘early estrogen response’ genes and stably interacts with RNAPII. Primarily based on the observations introduced right here, we suggest that phosphorylation at S187 by CDK9 represents an early occasion required for gene activation. This occasion may additionally be concerned within the launch of promoter-proximal polymerases to start elongation by interacting immediately with the polymerase or different components of the transcription equipment. Though we centered on estrogen-responsive genes, considering earlier proof of H1.4’s enrichment of promoters of pluripotency genes, and its involvement with rDNA activation, we suggest that H1.Four phosphorylation for gene activation could also be a extra world statement.

 A global analysis of low-complexity regions in the Trypanosoma brucei proteome reveals enrichment in the C-terminus of nucleic acid binding proteins providing potential targets of phosphorylation
A global analysis of low-complexity regions in the Trypanosoma brucei proteome reveals enrichment in the C-terminus of nucleic acid binding proteins providing potential targets of phosphorylation

Photosensitive tyrosine analogues unravel site-dependent phosphorylation in TrkA initiated MAPK/ERK signaling

Tyrosine kinase A (TrkA) is a membrane receptor which, upon ligand binding, prompts a number of pathways together with MAPK/ERK signaling, implicated in a spectrum of human pathologies; thus, TrkA is an rising therapeutic goal in remedy of neuronal illnesses and most cancers. Nonetheless, mechanistic insights into TrKA signaling are missing on account of lack of site-dependent phosphorylation management.
Right here we engineer two light-sensitive tyrosine analogues, specifically p-azido-L-phenylalanine (AzF) and the caged-tyrosine (ONB), by means of amber codon suppression to optically manipulate the phosphorylation state of particular person intracellular tyrosines in TrkA. We establish TrkA-AzF and ONB mutants, which may activate the ERK pathway within the absence of NGF ligand binding by means of gentle management. Our outcomes not solely reveal how TrkA site-dependent phosphorylation controls the outlined signaling course of, but in addition lengthen the genetic code growth expertise to allow regulation of receptor-type kinase activation by optical management on the precision of a single phosphorylation website.

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Description: A Rabbit Polyclonal antibody against ?-SMA from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

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Description: A Rabbit Polyclonal antibody against ?-SMA from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

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Description: A Rabbit Polyclonal antibody against ?-SMA from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

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Description: A Rabbit Polyclonal antibody against ?-SMA from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

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Description: A Rabbit Polyclonal antibody against ?-SMA from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

?-SMA Polyclonal Antibody

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Description: A Rabbit Polyclonal antibody against ?-SMA from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

?-SMA Polyclonal Antibody

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Description: A Rabbit Polyclonal antibody against ?-SMA from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

?-SMA Polyclonal Antibody

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Description: A Rabbit Polyclonal antibody against ?-SMA from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

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  • Immunogen information: Synthesized peptide derived from the N-terminal region of human ?-SMA
  • Applications tips:
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Alpha-SMA Polyclonal Antibody

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  • Immunogen information: Synthesized peptide derived from the N-terminal region of human ?-SMA
  • Applications tips:
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Alpha-SMA Polyclonal Antibody

ABP52784-02ml Abbkine 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from the N-terminal region of human ?-SMA
  • Applications tips:
Description: A polyclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human ?-SMA

Alpha-SMA Polyclonal Antibody

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EUR 158
  • Immunogen information: Synthesized peptide derived from the C-terminal region of human ?-SMA
  • Applications tips:
Description: A polyclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human ?-SMA

Alpha-SMA Polyclonal Antibody

ABP52851-01ml Abbkine 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from the C-terminal region of human ?-SMA
  • Applications tips:
Description: A polyclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human ?-SMA

Alpha-SMA Polyclonal Antibody

ABP52851-02ml Abbkine 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from the C-terminal region of human ?-SMA
  • Applications tips:
Description: A polyclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human ?-SMA

Alpha-SMA Polyclonal Antibody

ABP52852-003ml Abbkine 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from the Internal region of human ?-SMA
  • Applications tips:
Description: A polyclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ?-SMA

Alpha-SMA Polyclonal Antibody

ABP52852-01ml Abbkine 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from the Internal region of human ?-SMA
  • Applications tips:
Description: A polyclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ?-SMA

Alpha-SMA Polyclonal Antibody

ABP52852-02ml Abbkine 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from the Internal region of human ?-SMA
  • Applications tips:
Description: A polyclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ?-SMA

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  • Immunogen information: Synthesized peptide derived from ?-SMA at AA range: 171-220
  • Applications tips:
Description: A polyclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from ?-SMA at AA range: 171-220

Alpha-SMA Polyclonal Antibody

ABP57522-01ml Abbkine 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from ?-SMA at AA range: 171-220
  • Applications tips:
Description: A polyclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from ?-SMA at AA range: 171-220

Alpha-SMA Polyclonal Antibody

ABP57522-02ml Abbkine 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from ?-SMA at AA range: 171-220
  • Applications tips:
Description: A polyclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from ?-SMA at AA range: 171-220

Alpha-SMA Monoclonal Antibody

ABM40185-003ml Abbkine 0.03ml
EUR 158
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Alpha-SMA Monoclonal Antibody

ABM40185-01ml Abbkine 0.1ml
EUR 289
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Alpha-SMA Monoclonal Antibody

ABM40185-02ml Abbkine 0.2ml
EUR 414
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Alpha-SMA Monoclonal Antibody

ABM40186-003ml Abbkine 0.03ml
EUR 158
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IF, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Alpha-SMA Monoclonal Antibody

ABM40186-01ml Abbkine 0.1ml
EUR 289
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IF, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Alpha-SMA Monoclonal Antibody

ABM40186-02ml Abbkine 0.2ml
EUR 414
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IF, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

Anti- alpha-SMA Antibody

A03744 BosterBio 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for alpha-SMA Antibody (ACTC1) detection.tested for IHC-P, WB in Human, Mouse, Rat.

α-SMA Polyclonal Antibody

41550-100ul SAB 100ul
EUR 252

α-SMA Polyclonal Antibody

41550-50ul SAB 50ul
EUR 187

α-SMA Monoclonal Antibody

40482-100ul SAB 100ul
EUR 252

α-SMA Monoclonal Antibody

40482-50ul SAB 50ul
EUR 187

α-SMA Monoclonal Antibody

40495-100ul SAB 100ul
EUR 252

α-SMA Monoclonal Antibody

40495-50ul SAB 50ul
EUR 187

Anti-alpha-SMA antibody

STJ97381 St John's Laboratory 200 µl
EUR 197
Description: Mouse monoclonal to alpha-SMA.

Anti-alpha-SMA antibody

STJ97382 St John's Laboratory 200 µl
EUR 197
Description: alpha-SMA is a protein encoded by the ACTA2 gene which is approximately 42 kDa. alpha-SMA is localised to the cytoplasm and cytoskeleton. It is involved in the PAK pathway, VEGF pathway, fMLP pathway and Sertoli-Sertoli cell junction dynamics. This protein falls under the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. It is an alpha actin that is found in skeletal muscle. alpha-SMA is expressed in the muscle, lung, nervous system, intestine and pancreas. Mutations in the ACTA2 gene may result in Moyamoya disease. STJ97382 was developed from clone 6A12 and was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. The antibody detects endogenous alpha-SMA protein.

Anti-alpha-SMA antibody

STJ98628 St John's Laboratory 200 µl
EUR 197
Description: alpha-SMA is a protein encoded by the ACTA2 gene which is approximately 42 kDa. alpha-SMA is localised to the cytoplasm and cytoskeleton. It is involved in the PAK pathway, VEGF pathway, fMLP pathway and Sertoli-Sertoli cell junction dynamics. This protein falls under the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. This protein is an alpha actin that is found in skeletal muscle and is a major constituent of the contractile apparatus. alpha-SMA is expressed in the muscle, lung, nervous system, intestine and pancreas. Mutations in the ACTA2 gene may result in Moyamoya disease. STJ98628 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of alpha-SMA.

Anti-alpha-SMA antibody

STJ96418 St John's Laboratory 200 µl
EUR 197
Description: Rabbit polyclonal to alpha-SMA.

Anti-alpha-SMA antibody

STJ96485 St John's Laboratory 200 µl
EUR 197
Description: Rabbit polyclonal to alpha-SMA.

Anti-alpha-SMA antibody

STJ96486 St John's Laboratory 200 µl
EUR 197
Description: Rabbit polyclonal to alpha-SMA.

Sma I unit: 1500

YRSMA1 Yeastern Biotech 1 vial Ask for price

HIS Lite™ Cy3 Bis NTA-Ni Complex

12610 AAT Bioquest 1 mg
EUR 393
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

HIS Lite™ Cy5 Bis NTA-Ni Complex

12613 AAT Bioquest 1 mg
EUR 393
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Human Protection Of Telomeres 1 Homolog (POT1) Protein

20-abx654836 Abbexa
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Protection of Telomeres Protein 1 (POT1) Antibody (HRP)

20-abx317652 Abbexa
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Protection of Telomeres Protein 1 (POT1) Antibody (FITC)

20-abx317653 Abbexa
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Protection of Telomeres Protein 1 (POT1) Antibody (Biotin)

20-abx317654 Abbexa
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

α-SMA Polyclonal Conjugated Antibody

C41550 SAB 100ul
EUR 397

Goat α-SMA ELISA Kit

EGTS0011 Abclonal 96Tests
EUR 521

Bovine α-SMA ELISA Kit

EBS0011 Abclonal 96Tests
EUR 521

Chicken α-SMA ELISA Kit

ECKS0011 Abclonal 96Tests
EUR 521

Anserini α-SMA ELISA Kit

EAS0011 Abclonal 96Tests
EUR 521

Canine α-SMA ELISA Kit

ECS0011 Abclonal 96Tests
EUR 521

Porcine α-SMA ELISA Kit

EPS0011 Abclonal 96Tests
EUR 521

Rat α-SMA ELISA Kit

ERS0011 Abclonal 96Tests
EUR 521

Sheep α-SMA ELISA Kit

ESS0011 Abclonal 96Tests
EUR 521

Rabbit α-SMA ELISA Kit

ERTS0011 Abclonal 96Tests
EUR 521

Monkey α-SMA ELISA Kit

EMKS0011 Abclonal 96Tests
EUR 521

Mouse α-SMA ELISA Kit

EMS0011 Abclonal 96Tests
EUR 521

Blu-Lite UHC Autoradiography film, 5x7in, 100 sheets/box

A8813 MTC Bio 1 box
EUR 103.33
Description: Autoradiography Film

Blu-Lite UHC Autoradiography film, 8x10in, 100 sheets/box

A8815 MTC Bio 1 box
EUR 120.88
Description: Autoradiography Film

Human Protection Of Telomeres 1 Homolog (POT1) CLIA Kit

20-abx495819 Abbexa
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.

Human Protection of Telomeres Protein 1 (POT1) ELISA Kit

abx572962-96tests Abbexa 96 tests
EUR 786
  • Shipped within 5-12 working days.

Human Protection of telomeres protein 1, POT1 ELISA KIT

ELI-36535h Lifescience Market 96 Tests
EUR 824

Chicken Protection of telomeres protein 1, POT1 ELISA KIT

ELI-45371c Lifescience Market 96 Tests
EUR 928

Mouse Protection of telomeres protein 1, Pot1 ELISA KIT

ELI-38106m Lifescience Market 96 Tests
EUR 865

Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit

20-abx152802 Abbexa
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit

DLR-POT1-Hu-48T DL Develop 48T
EUR 517
  • Should the Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Protection Of Telomeres 1 Homolog (POT1) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit

DLR-POT1-Hu-96T DL Develop 96T
EUR 673
  • Should the Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Protection Of Telomeres 1 Homolog (POT1) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit

RD-POT1-Hu-48Tests Reddot Biotech 48 Tests
EUR 521

Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit

RD-POT1-Hu-96Tests Reddot Biotech 96 Tests
EUR 723

Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit

RDR-POT1-Hu-48Tests Reddot Biotech 48 Tests
EUR 544

Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit

RDR-POT1-Hu-96Tests Reddot Biotech 96 Tests
EUR 756

Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit

SEK108Hu-10x96wellstestplate Cloud-Clone 10x96-wells test plate
EUR 4731.5
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Protection Of Telomeres 1 Homolog (POT1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-As
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Protection Of Telomeres 1 Homolog (POT1) in Tissue homogenates, cell lysates and other biological fluids.

Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit

SEK108Hu-1x48wellstestplate Cloud-Clone 1x48-wells test plate
EUR 477.3
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Protection Of Telomeres 1 Homolog (POT1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-As
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Protection Of Telomeres 1 Homolog (POT1) in Tissue homogenates, cell lysates and other biological fluids.

Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit

SEK108Hu-1x96wellstestplate Cloud-Clone 1x96-wells test plate
EUR 639
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Protection Of Telomeres 1 Homolog (POT1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-As
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Protection Of Telomeres 1 Homolog (POT1) in Tissue homogenates, cell lysates and other biological fluids.

Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit

SEK108Hu-5x96wellstestplate Cloud-Clone 5x96-wells test plate
EUR 2575.5
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Protection Of Telomeres 1 Homolog (POT1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-As
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Protection Of Telomeres 1 Homolog (POT1) in Tissue homogenates, cell lysates and other biological fluids.

Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit

4-SEK108Hu Cloud-Clone
  • EUR 4782.00
  • EUR 2526.00
  • EUR 640.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Protection Of Telomeres 1 Homolog elisa. Alternative names of the recognized antigen: hPot1
  • POT1-like telomere end-binding protein
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Protection Of Telomeres 1 Homolog (POT1) in samples from Tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Guinea Pig α-SMA ELISA Kit

EGS0011 Abclonal 96Tests
EUR 521

Anti-Actin, Smooth Muscle (SMA) antibody

STJ180001 St John's Laboratory 0.1 ml
EUR 212

ELISA kit for Human POT1 (Protection of Telomeres Protein 1)

E-EL-H1968 Elabscience Biotech 1 plate of 96 wells
EUR 534
  • Gentaur's POT1 ELISA kit utilizes the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human POT1. Standards or samples are added to the micro ELISA plate wells and combined with th
  • Show more
Description: A sandwich ELISA kit for quantitative measurement of Human POT1 (Protection of Telomeres Protein 1) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human POT1 (Protection Of Telomeres 1 Homolog)

ELK4349 ELK Biotech 1 plate of 96 wells
EUR 432
  • The microtiter plate provided in this kit has been pre-coated with an antibody specific to Protection Of Telomeres 1 Homolog (POT1). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody speci
  • Show more
Description: A sandwich ELISA kit for detection of Protection Of Telomeres 1 Homolog from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Pot1 Protection of Telomeres 1 Homolog (S. Pombe) (POT1) Antibody

20-abx114619 Abbexa
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

ELISA kit for Chicken Protection of telomeres protein 1 (POT1)

KTE30066-48T Abbkine 48T
EUR 354
  • POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere len
  • Show more
Description: Quantitative sandwich ELISA for measuring Chicken Protection of telomeres protein 1 (POT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Chicken Protection of telomeres protein 1 (POT1)

KTE30066-5platesof96wells Abbkine 5 plates of 96 wells
EUR 2252
  • POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere len
  • Show more
Description: Quantitative sandwich ELISA for measuring Chicken Protection of telomeres protein 1 (POT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Chicken Protection of telomeres protein 1 (POT1)

KTE30066-96T Abbkine 96T
EUR 572
  • POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere len
  • Show more
Description: Quantitative sandwich ELISA for measuring Chicken Protection of telomeres protein 1 (POT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Protection of telomeres protein 1 (POT1)

KTE70711-48T Abbkine 48T
EUR 332
  • POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere len
  • Show more
Description: Quantitative sandwich ELISA for measuring Mouse Protection of telomeres protein 1 (POT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Protection of telomeres protein 1 (POT1)

KTE70711-5platesof96wells Abbkine 5 plates of 96 wells
EUR 2115
  • POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere len
  • Show more
Description: Quantitative sandwich ELISA for measuring Mouse Protection of telomeres protein 1 (POT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Protection of telomeres protein 1 (POT1)

KTE70711-96T Abbkine 96T
EUR 539
  • POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere len
  • Show more
Description: Quantitative sandwich ELISA for measuring Mouse Protection of telomeres protein 1 (POT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

DNA Protection During Starvation Protein (dps) Antibody

20-abx319361 Abbexa
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Human Smooth Muscle Antibody (SMA) ELISA Kit

abx053673-96tests Abbexa 96 tests
EUR 668
  • Shipped within 5-10 working days.

Alpha-Smooth Muscle Actin (alpha SMA) Antibody

abx020127-100ug Abbexa 100 ug
EUR 439
  • Shipped within 5-10 working days.

Human ?-Smooth muscle actin,?-SMA ELISA Kit

201-12-1209 SunredBio 96 tests
EUR 440
  • This alpha -Smooth muscle actin ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Sma I -HC unit: 1500, High Concentration

YRSMA1-HC Yeastern Biotech 1 vial Ask for price

DNA Protection During Starvation Protein (DPS) Antibody (HRP)

20-abx319362 Abbexa
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

DNA Protection During Starvation Protein (DPS) Antibody (FITC)

20-abx319363 Abbexa
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

DNA Protection During Starvation Protein (DPS) Antibody (Biotin)

20-abx319364 Abbexa
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Mycobacterium smegmatis DNA protection during starvation protein (dps)

1-CSB-EP314354MVW Cusabio
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 36.3 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Mycobacterium smegmatis DNA protection during starvation protein(dps) expressed in E.coli

Helicobacter pylori DNA protection during starvation protein (dps)

1-CSB-EP337381HUV Cusabio
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 32.9 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Helicobacter pylori DNA protection during starvation protein(dps) expressed in E.coli

Guinea Pig α-Smooth muscle actin(α-SMA)

QY-E90128 Qayee Biotechnology 96T
EUR 478

Human α-Smooth muscle actin(α-SMA)ELISA Kit

GA-E1225HM-48T GenAsia Biotech 48T
EUR 289

Human α-Smooth muscle actin(α-SMA)ELISA Kit

GA-E1225HM-96T GenAsia Biotech 96T
EUR 466

Porcine α-Smooth muscle actin,α-SMA ELISA Kit

GA-E0079PC-48T GenAsia Biotech 48T
EUR 364

Porcine α-Smooth muscle actin,α-SMA ELISA Kit

GA-E0079PC-96T GenAsia Biotech 96T
EUR 590

Human Alpha-Smooth Muscle Actin (a-SMA) CLIA Kit

abx196431-96tests Abbexa 96 tests
EUR 825
  • Shipped within 5-12 working days.

Rat α-Smooth muscle actin, α-SMA ELISA Kit

CSB-E14027r-24T Cusabio 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Rat α-Smooth muscle actin, α-SMA in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat α-Smooth muscle actin, α-SMA ELISA Kit

1-CSB-E14027r Cusabio
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Rat α-Smooth muscle actin, α-SMA in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human α-Smooth muscle actin,α-SMA ELISA Kit

CN-04299H1 ChemNorm 96T
EUR 478

Human α-Smooth muscle actin,α-SMA ELISA Kit

CN-04299H2 ChemNorm 48T
EUR 329

Human α-Smooth muscle actin, α-SMA ELISA Kit

CSB-E09343h-24T Cusabio 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Human α-Smooth muscle actin, α-SMA in samples from serum, urine, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human α-Smooth muscle actin, α-SMA ELISA Kit

1-CSB-E09343h Cusabio
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Human α-Smooth muscle actin, α-SMA in samples from serum, urine, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
It paves the best way for complete evaluation of kinase-associated pathways in addition to screening of compounds intervening in a site-directed phosphorylation pathway for focused remedy.  Intermittent hypoxia (IH), a most important attribute of obstructive sleep apnea (OSA) syndrome, has been often known as a dominant explanation for OSA-related endothelial dysfunction and hypertension. Nonetheless, the underlying mechanism nonetheless stays unclear. Extracellular vesicles (EVs), small vesicles secreted by varied cells, may be absorbed by endothelial cells after which affect vascular operate. The goal of this analysis is to make clear whether or not and the way EVs shedding from purple blood cells (RBCs) are concerned in IH-induced endothelial dysfunction.

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  • STAT3 Phosphorylation Inhibition for Treating Inflammation and New Bone Formation in Ankylosing Spondylitis
  • Phosphorylation and Driver Mutations in PI3Kα and PTEN Autoinhibition
  • HPV 16 E6/E7 Promote the Glucose Uptake of GLUT1 in Lung Cancer Through Downregulation of TXNIP Due to Inhibition of PTEN Phosphorylation
  • Regulation of an important glycolytic enzyme, pyruvate kinase, through phosphorylation in the larvae of a species of freeze tolerant insect, Eurosta solidaginis
  • A global analysis of low-complexity regions in the Trypanosoma brucei proteome reveals enrichment in the C-terminus of nucleic acid binding proteins providing potential targets of phosphorylation
  • Myocardial Dysfunction in Cirrhotic Cardiomyopathy is Associated with Alterations of Phospholamban Phosphorylation and IL-6 Levels
  • Anti-Human Common beta chain
  • Glutathione Reductase Assay Kit
  • Culture Fluid for limit of detection determination
  • BK Virus Linearity control Panel

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Recent Posts

  • STAT3 Phosphorylation Inhibition for Treating Inflammation and New Bone Formation in Ankylosing Spondylitis
  • Phosphorylation and Driver Mutations in PI3Kα and PTEN Autoinhibition
  • HPV 16 E6/E7 Promote the Glucose Uptake of GLUT1 in Lung Cancer Through Downregulation of TXNIP Due to Inhibition of PTEN Phosphorylation
  • Regulation of an important glycolytic enzyme, pyruvate kinase, through phosphorylation in the larvae of a species of freeze tolerant insect, Eurosta solidaginis
  • A global analysis of low-complexity regions in the Trypanosoma brucei proteome reveals enrichment in the C-terminus of nucleic acid binding proteins providing potential targets of phosphorylation
  • Myocardial Dysfunction in Cirrhotic Cardiomyopathy is Associated with Alterations of Phospholamban Phosphorylation and IL-6 Levels
  • Anti-Human Common beta chain
  • Glutathione Reductase Assay Kit
  • Culture Fluid for limit of detection determination
  • BK Virus Linearity control Panel

Categories

  • Antibodies
  • Assay Kits
  • Biology Cells
  • cDNA
  • Clia Kits
  • Culture Cells
  • Devices
  • DNA
  • DNA Templates
  • Elisa Kits
  • Enzymes
  • Equipments
  • Exosomes
  • Gels
  • Isotypes
  • Medium & Serums
  • NATtrol
  • Panel
  • Particles
  • PCR
  • Pcr Kits
  • Peptides
  • Reagents
  • Recombinant Proteins
  • Ria Kits
  • RNA

Tags

antibodies and covid 19 antibodies covid antibodies defined antibodies definition antibodies for coronavirus antibodies for covid-19 antibodies in saliva antibodies in spanish antibodies song antibodies test antibodies test corona antibodies test covid antibodies test covid19 antibodies test for coronavirus antibodies testing antibodies testing coronavirus antibodies testing for covid19 antibodies test ohio antibodies types antibodies vs immunity dna ancestry dna block dna bts dna hr block dna hrblock login dnajlion7 youtube dnalion7 youtube dna lyrics dna motoring dna painter dna productions dna replication dna song dna testing kits dna tests rna-seq rna definition rnai rna polymerase rna reset rnascope rna structure rnation.riteaid.com rna vaccine rna vs dna
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