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HPV 16 E6/E7 Promote the Glucose Uptake of GLUT1 in Lung Cancer Through Downregulation of TXNIP Due to Inhibition of PTEN Phosphorylation

HPV 16 E6/E7 Promote the Glucose Uptake of GLUT1 in Lung Cancer Through Downregulation of TXNIP Due to Inhibition of PTEN Phosphorylation

Posted on December 10, 2020 by Christopher

Excessive-risk human papillomavirus (HPV) an infection play an essential position within the growth of lung most cancers. Our beforehand research confirmed that E6 and E7 in HPV16 upregulated the expression of GLUT1 in lung most cancers cells. Nonetheless, whether or not they can promote the glucose uptake by GLUT1 and the underlying molecular mechanism has not been recognized. It has been reported that thioredoxin interacting protein (TXNIP) regulates each the expression of GLUT1 and its glucose uptake.

We speculate that prime threat HPV16 an infection could also be intently associated to TXNIP expression. Due to this fact, we affiliate HPV16 with TXNIP to discover the potential molecular mechanism of their regulation of GLUT1 expression and glucose uptake. Utilizing double directional genetic manipulation in lung most cancers cells, we confirmed that HPV16 E6/E7 proteins downregulated the expression of p-PTEN in lung most cancers cells, the knockdown of PTEN additional inhibited the expression of TXNIP, the inhibition of TXNIP additional promoted the buildup of HIF-1α by inhibiting the translocation of nuclear HIF-1α to the cytoplasm, and subsequently upregulated the expression of GLUT1 on the protein and mRNA ranges. Extra curiously, we discovered that the knockdown of TXNIP performed a decisive position to advertise the glucose uptake by GLUT1. Collectively, these findings instructed that the PTEN-TXNIP-HIF-1α axis may be associated to the E6/E7-mediated expression of GLUT1 and its glucose uptake.

Mitochondria play an essential position in efficient cell vitality manufacturing and cell survival below stress situations, reminiscent of therapy with chemotherapeutic medicine. Mitochondrial biogenesis is elevated in ovarian most cancers tissues, which is accompanied by alteration of mitochondrial vitality metabolism, construction, and dynamics. These components are concerned in tumorigenesis and apoptosis resistance, highlighting the position of mitochondria in resisting cisplatin toxicity. Cisplatin-resistant ovarian most cancers cells are depending on mitochondrial OXPHOS for vitality provide, and intracellular PGC1α-mediated mitochondrial biogenesis ranges are elevated on this cell line, indicating the essential position of mitochondrial oxidative phosphorylation in cisplatin resistance.

 

 HPV 16 E6/E7 Promote the Glucose Uptake of GLUT1 in Lung Cancer Through Downregulation of TXNIP Due to Inhibition of PTEN Phosphorylation
HPV 16 E6/E7 Promote the Glucose Uptake of GLUT1 in Lung Cancer Through Downregulation of TXNIP Due to Inhibition of PTEN Phosphorylation

Key advances in biocatalytic phosphorylations within the final twenty years – Biocatalytic syntheses in vitro and biotransformations in vivo (in people)

Background: Biocatalytic phosphorylation reactions present a number of advantages, reminiscent of extra direct, milder, extra selective, and shorter entry routes to phosphorylated merchandise. Favorable traits of biocatalytic methodologies characterize benefits for in vitro in addition to for in vivo phosphorylation reactions, resulting in essential advances within the science of synthesis in the direction of bioactive phosphorylated compounds in varied areas.
Objective and scope: The scope of this evaluation covers key advances of biocatalytic phosphorylation reactions over the past twenty years, for biocatalytic syntheses in vitro and for biotransformations in vivo (in people). From the origins of probiotic life to in vitro artificial purposes and in vivo formation of bioactive prescribed drugs, the widespread objective is to stipulate the significance, relevance, and underlying connections of biocatalytic phosphorylations of small molecules. Uneven phosphorylations attracting elevated consideration are highlighted.
Abstract: Phosphohydrolases, phosphotransferases, phosphorylases, phosphomutases and different enzymes concerned in phosphorus chemistry present highly effective toolboxes for resource-efficient and selective in vitro biocatalytic syntheses of phosphorylated metabolites, chiral constructing blocks, prescribed drugs in addition to in vivo enzymatic formation of biologically energetic types of prescribed drugs.
Conclusion: Nature’s giant variety of phosphoryl-group-transferring enzymes, superior enzyme, and response engineering toolboxes make biocatalytic uneven phosphorylations utilizing enzymes a strong and privileged phosphorylation methodology. This text is protected by copyright. All rights reserved.
Key phrases: Enzymatic phosphorylation; chiral constructing blocks; kinases; metabolites; prescribed drugs; phosphatases; phosphomutases; phosphoryl-donor; phosphorylases; phosphotransferases.

Sphingolipids and Inositol Phosphates Regulate the Tau Protein Phosphorylation Standing in Humanized Yeast

Hyperphosphorylation of protein tau is a trademark of Alzheimer’s illness (AD). Adjustments in vitality and lipid metabolism have been correlated with the late onset of this neurological dysfunction. Nonetheless, it’s unsure if metabolic dysregulation is a consequence of AD or one of many initiating components of AD pathophysiology. Additionally, it’s unclear whether or not variations in lipid metabolism regulate the phosphorylation state of tau. Right here, we present that in humanized yeast, tau hyperphosphorylation is stimulated by glucose hunger in coincidence with the downregulation of Pho85, the yeast ortholog of CDK5. Adjustments in inositol phosphate (IP) signaling, which has a central position in vitality metabolism, altered tau phosphorylation.
Lack of inositol hexakisphosphate kinases Kcs1 and Vip1 (IP6 and IP7 kinases in mammals) elevated tau hyperphosphorylation. Related results had been discovered by mutation of IPK2 (inositol polyphosphate multikinase), or PLC1, the yeast phospholipase C gene. These results could also be defined by IP-mediated regulation of Pho85. Certainly, this seemed to be the case for plc1, ipk2, and kcs1. Nonetheless, the results of Vip1 on tau phosphorylation had been impartial of the presence of Pho85, suggesting further mechanisms. Apparently, kcs1 and vip1 strains, like pho85, displayed dysregulated sphingolipid (SL) metabolism.
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  • Immunogen information: Synthesized peptide derived from ?-SMA at AA range: 171-220
  • Applications tips:
Description: A polyclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from ?-SMA at AA range: 171-220
Alpha-SMA Polyclonal Antibody
ABP57522-02ml Abbkine 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from ?-SMA at AA range: 171-220
  • Applications tips:
Description: A polyclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from ?-SMA at AA range: 171-220
Alpha-SMA Monoclonal Antibody
ABM40185-003ml Abbkine 0.03ml
EUR 158
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide
Alpha-SMA Monoclonal Antibody
ABM40185-01ml Abbkine 0.1ml
EUR 289
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide
Alpha-SMA Monoclonal Antibody
ABM40185-02ml Abbkine 0.2ml
EUR 414
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide
Alpha-SMA Monoclonal Antibody
ABM40186-003ml Abbkine 0.03ml
EUR 158
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IF, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide
Alpha-SMA Monoclonal Antibody
ABM40186-01ml Abbkine 0.1ml
EUR 289
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IF, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide
Alpha-SMA Monoclonal Antibody
ABM40186-02ml Abbkine 0.2ml
EUR 414
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of Alpha-SMA from Human, Mouse, Rat. This Alpha-SMA antibody is for WB, IF, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide
Anti- alpha-SMA Antibody
A03744 BosterBio 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for alpha-SMA Antibody (ACTC1) detection.tested for IHC-P, WB in Human, Mouse, Rat.
α-SMA Polyclonal Antibody
41550-100ul SAB 100ul
EUR 252
α-SMA Polyclonal Antibody
41550-50ul SAB 50ul
EUR 187
α-SMA Monoclonal Antibody
40482-100ul SAB 100ul
EUR 252
α-SMA Monoclonal Antibody
40482-50ul SAB 50ul
EUR 187
α-SMA Monoclonal Antibody
40495-100ul SAB 100ul
EUR 252
α-SMA Monoclonal Antibody
40495-50ul SAB 50ul
EUR 187
Anti-alpha-SMA antibody
STJ97381 St John's Laboratory 200 µl
EUR 197
Description: Mouse monoclonal to alpha-SMA.
Anti-alpha-SMA antibody
STJ97382 St John's Laboratory 200 µl
EUR 197
Description: alpha-SMA is a protein encoded by the ACTA2 gene which is approximately 42 kDa. alpha-SMA is localised to the cytoplasm and cytoskeleton. It is involved in the PAK pathway, VEGF pathway, fMLP pathway and Sertoli-Sertoli cell junction dynamics. This protein falls under the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. It is an alpha actin that is found in skeletal muscle. alpha-SMA is expressed in the muscle, lung, nervous system, intestine and pancreas. Mutations in the ACTA2 gene may result in Moyamoya disease. STJ97382 was developed from clone 6A12 and was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. The antibody detects endogenous alpha-SMA protein.
Anti-alpha-SMA antibody
STJ98628 St John's Laboratory 200 µl
EUR 197
Description: alpha-SMA is a protein encoded by the ACTA2 gene which is approximately 42 kDa. alpha-SMA is localised to the cytoplasm and cytoskeleton. It is involved in the PAK pathway, VEGF pathway, fMLP pathway and Sertoli-Sertoli cell junction dynamics. This protein falls under the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. This protein is an alpha actin that is found in skeletal muscle and is a major constituent of the contractile apparatus. alpha-SMA is expressed in the muscle, lung, nervous system, intestine and pancreas. Mutations in the ACTA2 gene may result in Moyamoya disease. STJ98628 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of alpha-SMA.
Anti-alpha-SMA antibody
STJ96418 St John's Laboratory 200 µl
EUR 197
Description: Rabbit polyclonal to alpha-SMA.
Anti-alpha-SMA antibody
STJ96485 St John's Laboratory 200 µl
EUR 197
Description: Rabbit polyclonal to alpha-SMA.
Anti-alpha-SMA antibody
STJ96486 St John's Laboratory 200 µl
EUR 197
Description: Rabbit polyclonal to alpha-SMA.
Sma I unit: 1500
YRSMA1 Yeastern Biotech 1 vial Ask for price
Human Protection Of Telomeres 1 Homolog (POT1) Protein
20-abx654836 Abbexa
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.
Protection of Telomeres Protein 1 (POT1) Antibody (HRP)
20-abx317652 Abbexa
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.
Protection of Telomeres Protein 1 (POT1) Antibody (FITC)
20-abx317653 Abbexa
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.
Protection of Telomeres Protein 1 (POT1) Antibody (Biotin)
20-abx317654 Abbexa
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.
α-SMA Polyclonal Conjugated Antibody
C41550 SAB 100ul
EUR 397
Goat α-SMA ELISA Kit
EGTS0011 Abclonal 96Tests
EUR 521
Bovine α-SMA ELISA Kit
EBS0011 Abclonal 96Tests
EUR 521
Chicken α-SMA ELISA Kit
ECKS0011 Abclonal 96Tests
EUR 521
Anserini α-SMA ELISA Kit
EAS0011 Abclonal 96Tests
EUR 521
Canine α-SMA ELISA Kit
ECS0011 Abclonal 96Tests
EUR 521
Porcine α-SMA ELISA Kit
EPS0011 Abclonal 96Tests
EUR 521
Rat α-SMA ELISA Kit
ERS0011 Abclonal 96Tests
EUR 521
Sheep α-SMA ELISA Kit
ESS0011 Abclonal 96Tests
EUR 521
Rabbit α-SMA ELISA Kit
ERTS0011 Abclonal 96Tests
EUR 521
Monkey α-SMA ELISA Kit
EMKS0011 Abclonal 96Tests
EUR 521
Mouse α-SMA ELISA Kit
EMS0011 Abclonal 96Tests
EUR 521
Human Protection Of Telomeres 1 Homolog (POT1) CLIA Kit
20-abx495819 Abbexa
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.
Human Protection of Telomeres Protein 1 (POT1) ELISA Kit
abx572962-96tests Abbexa 96 tests
EUR 786
  • Shipped within 5-12 working days.
Human Protection of telomeres protein 1, POT1 ELISA KIT
ELI-36535h Lifescience Market 96 Tests
EUR 824
Chicken Protection of telomeres protein 1, POT1 ELISA KIT
ELI-45371c Lifescience Market 96 Tests
EUR 928
Mouse Protection of telomeres protein 1, Pot1 ELISA KIT
ELI-38106m Lifescience Market 96 Tests
EUR 865
Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit
20-abx152802 Abbexa
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.
Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit
DLR-POT1-Hu-48T DL Develop 48T
EUR 517
  • Should the Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Protection Of Telomeres 1 Homolog (POT1) in samples from tissue homogenates, cell lysates or other biological fluids.
Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit
DLR-POT1-Hu-96T DL Develop 96T
EUR 673
  • Should the Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Protection Of Telomeres 1 Homolog (POT1) in samples from tissue homogenates, cell lysates or other biological fluids.
Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit
RD-POT1-Hu-48Tests Reddot Biotech 48 Tests
EUR 521
Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit
RD-POT1-Hu-96Tests Reddot Biotech 96 Tests
EUR 723
Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit
RDR-POT1-Hu-48Tests Reddot Biotech 48 Tests
EUR 544
Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit
RDR-POT1-Hu-96Tests Reddot Biotech 96 Tests
EUR 756
Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit
SEK108Hu-10x96wellstestplate Cloud-Clone 10x96-wells test plate
EUR 4731.5
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Protection Of Telomeres 1 Homolog (POT1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-As
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Protection Of Telomeres 1 Homolog (POT1) in Tissue homogenates, cell lysates and other biological fluids.
Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit
SEK108Hu-1x48wellstestplate Cloud-Clone 1x48-wells test plate
EUR 477.3
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Protection Of Telomeres 1 Homolog (POT1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-As
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Protection Of Telomeres 1 Homolog (POT1) in Tissue homogenates, cell lysates and other biological fluids.
Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit
SEK108Hu-1x96wellstestplate Cloud-Clone 1x96-wells test plate
EUR 639
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Protection Of Telomeres 1 Homolog (POT1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-As
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Protection Of Telomeres 1 Homolog (POT1) in Tissue homogenates, cell lysates and other biological fluids.
Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit
SEK108Hu-5x96wellstestplate Cloud-Clone 5x96-wells test plate
EUR 2575.5
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Protection Of Telomeres 1 Homolog (POT1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-As
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Protection Of Telomeres 1 Homolog (POT1) in Tissue homogenates, cell lysates and other biological fluids.
Human Protection Of Telomeres 1 Homolog (POT1) ELISA Kit
4-SEK108Hu Cloud-Clone
  • EUR 4782.00
  • EUR 2526.00
  • EUR 640.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Protection Of Telomeres 1 Homolog elisa. Alternative names of the recognized antigen: hPot1
  • POT1-like telomere end-binding protein
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Protection Of Telomeres 1 Homolog (POT1) in samples from Tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species.
Guinea Pig α-SMA ELISA Kit
EGS0011 Abclonal 96Tests
EUR 521
Anti-Actin, Smooth Muscle (SMA) antibody
STJ180001 St John's Laboratory 0.1 ml
EUR 212
ELISA kit for Human POT1 (Protection of Telomeres Protein 1)
E-EL-H1968 Elabscience Biotech 1 plate of 96 wells
EUR 534
  • Gentaur's POT1 ELISA kit utilizes the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human POT1. Standards or samples are added to the micro ELISA plate wells and combined with th
  • Show more
Description: A sandwich ELISA kit for quantitative measurement of Human POT1 (Protection of Telomeres Protein 1) in samples from Serum, Plasma, Cell supernatant
ELISA kit for Human POT1 (Protection Of Telomeres 1 Homolog)
ELK4349 ELK Biotech 1 plate of 96 wells
EUR 432
  • The microtiter plate provided in this kit has been pre-coated with an antibody specific to Protection Of Telomeres 1 Homolog (POT1). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody speci
  • Show more
Description: A sandwich ELISA kit for detection of Protection Of Telomeres 1 Homolog from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.
Pot1 Protection of Telomeres 1 Homolog (S. Pombe) (POT1) Antibody
20-abx114619 Abbexa
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.
ELISA kit for Chicken Protection of telomeres protein 1 (POT1)
KTE30066-48T Abbkine 48T
EUR 354
  • POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere len
  • Show more
Description: Quantitative sandwich ELISA for measuring Chicken Protection of telomeres protein 1 (POT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Chicken Protection of telomeres protein 1 (POT1)
KTE30066-5platesof96wells Abbkine 5 plates of 96 wells
EUR 2252
  • POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere len
  • Show more
Description: Quantitative sandwich ELISA for measuring Chicken Protection of telomeres protein 1 (POT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Chicken Protection of telomeres protein 1 (POT1)
KTE30066-96T Abbkine 96T
EUR 572
  • POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere len
  • Show more
Description: Quantitative sandwich ELISA for measuring Chicken Protection of telomeres protein 1 (POT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Mouse Protection of telomeres protein 1 (POT1)
KTE70711-48T Abbkine 48T
EUR 332
  • POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere len
  • Show more
Description: Quantitative sandwich ELISA for measuring Mouse Protection of telomeres protein 1 (POT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Mouse Protection of telomeres protein 1 (POT1)
KTE70711-5platesof96wells Abbkine 5 plates of 96 wells
EUR 2115
  • POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere len
  • Show more
Description: Quantitative sandwich ELISA for measuring Mouse Protection of telomeres protein 1 (POT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Mouse Protection of telomeres protein 1 (POT1)
KTE70711-96T Abbkine 96T
EUR 539
  • POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere len
  • Show more
Description: Quantitative sandwich ELISA for measuring Mouse Protection of telomeres protein 1 (POT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
DNA Protection During Starvation Protein (dps) Antibody
20-abx319361 Abbexa
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.
Human Smooth Muscle Antibody (SMA) ELISA Kit
abx053673-96tests Abbexa 96 tests
EUR 668
  • Shipped within 5-10 working days.
Alpha-Smooth Muscle Actin (alpha SMA) Antibody
abx020127-100ug Abbexa 100 ug
EUR 439
  • Shipped within 5-10 working days.
Human ?-Smooth muscle actin,?-SMA ELISA Kit
201-12-1209 SunredBio 96 tests
EUR 440
  • This alpha -Smooth muscle actin ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.
Sma I -HC unit: 1500, High Concentration
YRSMA1-HC Yeastern Biotech 1 vial Ask for price
DNA Protection During Starvation Protein (DPS) Antibody (HRP)
20-abx319362 Abbexa
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.
DNA Protection During Starvation Protein (DPS) Antibody (FITC)
20-abx319363 Abbexa
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.
DNA Protection During Starvation Protein (DPS) Antibody (Biotin)
20-abx319364 Abbexa
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.
Mycobacterium smegmatis DNA protection during starvation protein (dps)
1-CSB-EP314354MVW Cusabio
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 36.3 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Mycobacterium smegmatis DNA protection during starvation protein(dps) expressed in E.coli
Helicobacter pylori DNA protection during starvation protein (dps)
1-CSB-EP337381HUV Cusabio
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 32.9 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Helicobacter pylori DNA protection during starvation protein(dps) expressed in E.coli
Guinea Pig α-Smooth muscle actin(α-SMA)
QY-E90128 Qayee Biotechnology 96T
EUR 478
Human α-Smooth muscle actin(α-SMA)ELISA Kit
GA-E1225HM-48T GenAsia Biotech 48T
EUR 289
Human α-Smooth muscle actin(α-SMA)ELISA Kit
GA-E1225HM-96T GenAsia Biotech 96T
EUR 466
Porcine α-Smooth muscle actin,α-SMA ELISA Kit
GA-E0079PC-48T GenAsia Biotech 48T
EUR 364
Porcine α-Smooth muscle actin,α-SMA ELISA Kit
GA-E0079PC-96T GenAsia Biotech 96T
EUR 590
Human Alpha-Smooth Muscle Actin (a-SMA) CLIA Kit
abx196431-96tests Abbexa 96 tests
EUR 825
  • Shipped within 5-12 working days.
Rat α-Smooth muscle actin, α-SMA ELISA Kit
CSB-E14027r-24T Cusabio 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Rat α-Smooth muscle actin, α-SMA in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Rat α-Smooth muscle actin, α-SMA ELISA Kit
1-CSB-E14027r Cusabio
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Rat α-Smooth muscle actin, α-SMA in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Human α-Smooth muscle actin,α-SMA ELISA Kit
CN-04299H1 ChemNorm 96T
EUR 478
Human α-Smooth muscle actin,α-SMA ELISA Kit
CN-04299H2 ChemNorm 48T
EUR 329
Human α-Smooth muscle actin, α-SMA ELISA Kit
CSB-E09343h-24T Cusabio 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Human α-Smooth muscle actin, α-SMA in samples from serum, urine, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Human α-Smooth muscle actin, α-SMA ELISA Kit
1-CSB-E09343h Cusabio
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Human α-Smooth muscle actin, α-SMA in samples from serum, urine, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Human α-Smooth muscle actin(α-SMA)ELISA Kit
QY-E04434 Qayee Biotechnology 96T
EUR 361
ELISA Microplate Reader (compact, 8 channel, automated, programmable) with 4 filters & ELISA reader software
MPR-404 Alpha Diagnostics 1
EUR 5531
ELISA Microplate Reader (compact, 8 channel, automated, programmable) with 6 filters & ELISA reader software
MPR-406 Alpha Diagnostics 1
EUR 5896
ELISA kit for Human Alpha2-Smooth muscle actin (Alpha2-SMA)
KTE60890-48T Abbkine 48T
EUR 354
Description: Quantitative sandwich ELISA for measuring Human Alpha2-Smooth muscle actin (Alpha2-SMA) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Human Alpha2-Smooth muscle actin (Alpha2-SMA)
KTE60890-5platesof96wells Abbkine 5 plates of 96 wells
EUR 2252
Description: Quantitative sandwich ELISA for measuring Human Alpha2-Smooth muscle actin (Alpha2-SMA) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Human Alpha2-Smooth muscle actin (Alpha2-SMA)
KTE60890-96T Abbkine 96T
EUR 572
Description: Quantitative sandwich ELISA for measuring Human Alpha2-Smooth muscle actin (Alpha2-SMA) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
AgileReader? ELISA Plate Reader 400-900nm, includes 405, 450, 490 and 600 filters and software
ACT-AMPR900A ACTGene
EUR 6805
AgileReader? ELISA Plate Reader 340-900nm, includes 340, 405, 450, 490 and 600 filters and software
ACT-AMPR900B ACTGene
EUR 7529
Neuregulin/Heregulin-1? (NRG-1?/HRG-1?), human recombinant protein
P1054-1 ApexBio 1 mg
EUR 3947
Description: Neuregulin (NRG) is a signaling protein for ErbB2/ErbB4 receptor heterodimers on the cardiac muscle cells and plays an important role in heart structure and function through inducing cardiomyocyte differentiation
Angiotensin 1/2 (1-7) amide
A1054-1 ApexBio 1 mg
EUR 96
Description: Angiotensin I/II (1-7) amide (H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-amide) is a peptide analog to angiotensin II that is used as a vasopressor in the treatment of certain types of shock and circulatory collapse.
Angiotensin 1/2 (1-8) amide
A1055-1 ApexBio 1 mg
EUR 96
Description: The physiologically active peptide angiotensin-2 (angiotensin 1- 8) is yielded from angiotensin-1, a substrate of ACE (angiotensin converting enzyme), by removing a dipeptide.
Endothelin-1 (1-15), amide, human
A1111-1 ApexBio 1 mg
EUR 722
Description: Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium and have a key role in vascular homeostasis.
Furthermore, genetic and pharmacological inhibition of SL biosynthesis stimulated the looks of hyperphosphorylated types of tau, whereas elevated flux via the pathway lowered its abundance. Lastly, we demonstrated that Sit4, the yeast ortholog of human PP2A protein phosphatase, is a downstream effector of SL signaling in mediating the tau phosphorylation state. Altogether, our outcomes add new data on the molecular effectors concerned in tauopathies and establish new targets for pharmacological intervention.

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Recent Posts

  • STAT3 Phosphorylation Inhibition for Treating Inflammation and New Bone Formation in Ankylosing Spondylitis
  • Phosphorylation and Driver Mutations in PI3Kα and PTEN Autoinhibition
  • HPV 16 E6/E7 Promote the Glucose Uptake of GLUT1 in Lung Cancer Through Downregulation of TXNIP Due to Inhibition of PTEN Phosphorylation
  • Regulation of an important glycolytic enzyme, pyruvate kinase, through phosphorylation in the larvae of a species of freeze tolerant insect, Eurosta solidaginis
  • A global analysis of low-complexity regions in the Trypanosoma brucei proteome reveals enrichment in the C-terminus of nucleic acid binding proteins providing potential targets of phosphorylation
  • Myocardial Dysfunction in Cirrhotic Cardiomyopathy is Associated with Alterations of Phospholamban Phosphorylation and IL-6 Levels
  • Anti-Human Common beta chain
  • Glutathione Reductase Assay Kit
  • Culture Fluid for limit of detection determination
  • BK Virus Linearity control Panel

Categories

  • Antibodies
  • Assay Kits
  • Biology Cells
  • cDNA
  • Clia Kits
  • Culture Cells
  • Devices
  • DNA
  • DNA Templates
  • Elisa Kits
  • Enzymes
  • Equipments
  • Exosomes
  • Gels
  • Isotypes
  • Medium & Serums
  • NATtrol
  • Panel
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  • Peptides
  • Reagents
  • Recombinant Proteins
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  • RNA

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